Get Skeleton Key as soon as possible. Next priority is upgrading No Stone Unturned to find Skeleton Key.

XP to upgrade

2xp

Burglary, Cryptic Writings, Emergence Cache, Ethereal Slip, Holy Rosary, Preposterous Sketches, Working a Hunch

3xp

Flashlight, Old Keyring, Scroll of Secrets

5xp

No Stone Unturned

1xp

Honed Instinct, Hunter's Armor, The Raven Quill, Emergency Cache 2 up to 3

Transmutation Targets

Need Willpower

• Agnes Baker - Mystic - 6/8
  deal damage when take sanity
  backup agility
• Akachi Onyele - Mystic - 6/8
  Assets come in with +1 charge
  Backup combat agility
• Dexter Drake - Mystic - 6/8
  Discard an asset to play an asset at for 1 less
  backup combat
• Jacqueline Fine - Mystic - 6/9
  once per round reveal 3 tokens and pick one
  backup Intellect

Need Intellect

• Daisy Walker - Seeker - 5/9
  Free Tome action
  backup Willpower
• Darrell Simmons - Survivor - 6/8
  none
  backup agility
• Harvey Walters - Seeker - 7/8
  reaction to card draw draw 1 extra
  backup Willpower
• Mandy Thompson - Seeker - 6/8
  if searching a deck either search 3 deeper or target 1 more
  backup willpower agility
• Norman Withers - Seeker - 6/8
  play with top of deck revealed and play at -1 cost
  backup willpower

Need Combat

• Daniela Reyes - Guardian - 8/6
  Reaction if attacked deal 1 damage or evade
  backup willpower
• Mark Harrigan - Guardian - 9/5
  doom on your asset draw a card
  backup willpower agility
• Michael McGlen - Rogue - 9/5
  firearm related
  backup willpower agility
• Nathaniel Cho - Guardian - 9/6
  once per phase do 1 more damage
  backup willpower
• Tony Morgan - Rogue - 9/5
  extra action to engage or fight
  backup Intellect

Need Agility

• Lucius Galloway - Seeker - 8/6
  after evading an enemy by 2 or more discover 1 clue
  backup Intellect
• Monterey Jack - Rogue - 8/6
  if in different location than start draw a card or make a resource
  backup Intellect
• Rita Young - Survivor - 9/5
  after evading an enemy deal 1 damage or move 1 time
  backup Willpower Combat
• Winifred Habbamock - Rogue - 8/7
  once per test draw a card if you committed 2 or more cards
  backup Intellect

4s in at least 2 things

• Agatha Crane - Seeker Mystic - 6/8
  4/4/1/3 - benefits for sealing tokens
• Alessandra Zorzi - Rogue - 7/7
  3/4/2/4 - Free Parlay
• Finn Edwards - Rogue - 7/7
  1/4/3/4 - Free Evade
• Joe Diamond - Seeker - 8/6
  2/4/4/2 - none
• Leo Anderson - Guardian - 8/6
  4/3/4/1 - 1 per turn asset costs 1 less
• Lucius Galloway - Seeker - 8/6
  2/4/1/5 - after evading an enemy by 2 or more discover 1 clue
• Marie Lambeau - Mystic - 6/8
  4/4/1/3 - none
• Minh Thi Phan - Seeker - 7/7
  4/4/2/2 - once per investigator per round committed cards get 1 more ?
• Monterey Jack - Rogue - 8/6
  1/4/2/5 - if in different location than start draw a card or make a resource
• Norman Withers - Seeker - 6/8
  4/5/2/1 - play with top of deck revealed and play at -1 cost
• Sefina Rousseau - Rogue - 5/9
  4/2/2/4 - none
• Silas Marsh - Survivor - 9/5
  2/2/4/4 - return committed skills to hand
• Trish Scarborough - Rogue - 8/6
  2/4/2/4 - after discovering a clue at an enemy location discover 1 more or evade
• Ursula Downs - Seeker - 7/7
  3/4/1/4 - After moving 1 free investigate
• Wendy Adams - Survivor - 7/7
  4/3/1/4 - Once per test discard a card from your hand to redraw from the bag
• Zoey Samaras - Guardian - 9/6
  4/2/4/2 - engage an enemy draw a card

Cool Ability Targets

• Jenny Barnes - Rogue - 8/7
  1 extra resource during upkeep
• Jim Culver - Mystic - 7/8
  Skulls are "0"s
• Mandy Thompson - Seeker - 6/8
  Scroll of Secrets becomes very powerful with her character ability
• Patrice Hathaway - Survivor - 7/7
  discard your hand and draw back to 5 every turn
• Rex Murphy - Seeker - 6/9
  if you succeed an investigation by 2 or more discover an extra clue
• Sister Mary - Guardian - 5/9
  add a blessing to the bag each round
• "Skids" O'Toole - Rogue - 8/6
  Pay 2 resources take and extra action
• Stella Clark - Survivor - 8/8
  If you fail a skill test take an extra action