
Okay, first off start with the basics. everyone knows that you shouldn't do Rex Murphy solo. You have been warned.
2ndly, it is really hard to get all of the cultists in midnight masks.
When playing a game with Rex Murphy you need to consider the following: 1. do I have someone to cover me? 2. is this scenario about clue gathering? if the answer to both of these is yes, then you will be pretty successful.
Rex's curse: To bypass the effects of this, what you need to do is always stack the odds in your favor. Have higher education and 5 or more cards in you hand with plenty of resources to feed it. It also helps if you have lots of cards that you can commit. this way, once you draw the second token you will have a very good chance of success.
Rex is all about clue gathering which makes him awesome for scenarios like Essex county express. There will be some monsters that your buddy can't get to fast enough so you want to pack I've got a plan.